Applications of L-Arginine in Pregnancy and Beyond: An Emerging Pharmacogenomic Approach (2024)

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Abstract

L-arginine is a semi-essential amino acid that plays a critical role in various physiologicalprocesses, such as protein synthesis, wound healing, immune function, and cardiovascular regulation.The use of L-arginine in pregnancy has been an emerging topic in the field of pharmacogenomics.L-arginine, an amino acid, plays a crucial role in the production of nitric oxide, which isnecessary for proper placental development and fetal growth. Studies have shown that L-argininesupplementation during pregnancy can have positive effects on fetal growth, maternal blood pressure,and the prevention of preeclampsia. This emerging pharmacogenomic approach involves usinggenetic information to personalize L-arginine dosages for pregnant women based on their specificgenetic makeup. By doing so, it may be possible to optimize the benefits of L-arginine supplementationduring pregnancy and improve pregnancy outcomes. This paper emphasizes the potentialapplications of L-arginine in pregnancy and the use of pharmacogenomic approaches to enhanceits effectiveness. Nonetheless, the emerging pharmacogenomic approach to the applicationof L-arginine offers exciting prospects for the development of novel therapies for a wide range ofdiseases.

Keywords: L-arginine, pregnancy, pharmacogenomics, nitric oxide, oligohydramnios, preeclampsia.

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Current Gene Therapy

Title:Applications of L-Arginine in Pregnancy and Beyond: An EmergingPharmacogenomic Approach

Volume: 24

Author(s): Sai Vaishnavi V*, Mahadevamma Lingaiah, Bala Murali Mohan Sanku, Sunil Kumar Kadiri and Manoj Kumar Mudigubba

Affiliation:

MLR Institute of Pharmacy, Hyderabad, India

Keywords: L-arginine, pregnancy, pharmacogenomics, nitric oxide, oligohydramnios, preeclampsia.

Abstract: L-arginine is a semi-essential amino acid that plays a critical role in various physiologicalprocesses, such as protein synthesis, wound healing, immune function, and cardiovascular regulation.The use of L-arginine in pregnancy has been an emerging topic in the field of pharmacogenomics.L-arginine, an amino acid, plays a crucial role in the production of nitric oxide, which isnecessary for proper placental development and fetal growth. Studies have shown that L-argininesupplementation during pregnancy can have positive effects on fetal growth, maternal blood pressure,and the prevention of preeclampsia. This emerging pharmacogenomic approach involves usinggenetic information to personalize L-arginine dosages for pregnant women based on their specificgenetic makeup. By doing so, it may be possible to optimize the benefits of L-arginine supplementationduring pregnancy and improve pregnancy outcomes. This paper emphasizes the potentialapplications of L-arginine in pregnancy and the use of pharmacogenomic approaches to enhanceits effectiveness. Nonetheless, the emerging pharmacogenomic approach to the applicationof L-arginine offers exciting prospects for the development of novel therapies for a wide range ofdiseases.

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Cite this article as:

V Sai Vaishnavi*, Lingaiah Mahadevamma, Sanku Bala Murali Mohan, Kadiri Sunil Kumar and Mudigubba Manoj Kumar, Applications of L-Arginine in Pregnancy and Beyond: An EmergingPharmacogenomic Approach, Current Gene Therapy 2024; 24 () . https://dx.doi.org/10.2174/0115665232262213240329034826

DOI https://dx.doi.org/10.2174/0115665232262213240329034826	Print ISSN 1566-5232
Publisher Name Bentham Science Publisher	Online ISSN 1875-5631

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